Current / ongoing studies

Below are current research studies being conducted at Cumbria Partnership NHS Foundation Trust.

Please have a look and see if you would be interested in becoming a participant or wish to obtain further information.

If none of these studies below are suitable, please feel free to register on the Making Research Better website to receive information about future studies.

For all the studies mentioned below please contact us via research@cumbria.nhs.uk or on tel 01228 603145 if you wish to discuss anything in more detail or want to express an interest.

Thank you for considering taking part.

CURRENT / ONGOING STUDIES

Below are current research studies being conducted at Cumbria Partnership NHS Foundation Trust.

Please have a look and see if you would be interested in becoming a participant or wish to obtain further information.

If none of these studies below are suitable, please feel free to register on the Making Research Better website to receive information about future studies.

For all the studies mentioned below please contact us via research@cumbria.nhs.uk or on tel 01228 603145 if you wish to discuss anything in more detail or want to express an interest.

Thank you for considering taking part.

BRAINCOOL – Migraine Trial

Cumbria Partnership NHS Foundation Trust is now conducting a trial of a novel migraine treatment utilising a ‘cooling device’. Current treatments for people with migraines do not always work and can cause side effects; there is an unmet need for new treatment options.

The trial is open to residents of Cumbria, Northumberland, Tyne & Wear, County Durham and Teesside and is looking for 90 participants from across the regions. This study is looking for people that have had 1 - 15 migraines a month (episodic migraine) for over a year and have had no changes to their migraine medication in the last three months. Participants should be aged 18 - 70 with no history of heart disease and no current or planned pregnancy. 

The BrainCool-Migraine trial aims to see how effective a treatment called ‘intra-nasal evaporative cooling’ is at helping to reduce the headache pain often associated with migraine. The treatment works by introducing cooling into the passageways of the nose through two small cannulas. It is believed that this cooling may cause blood vessels surrounding the brain to narrow, thus relieving the pain and symptoms of migraine. The cooling may also directly affect cell-signalling in the brain, which may stop a migraine headache.

“Among adults of all ages, migraine is one of the top 20 causes of disability. It is becoming increasingly important to find novel, drug-free, methods to treat migraine headache. A recent pilot trial has shown that ‘intra-nasal cooling’ appears to be an effective, quick and well-tolerated treatment. Our team is now starting a larger ‘randomised’ clinical trial to provide further evidence of benefit from this application” commented Dr Vanderpol.

Participants who meet the criteria will be asked to complete a questionnaire relating to their migraines for a month to further assess if they can receive the new treatment. After this period, if suitable, participants will be given either a ‘BrainCool’ device or a ‘dummy’ device (placebo) for use during their next three migraines and will be asked to record some more information.

The device is manufactured by ‘BrainCool AB’ from Sweden. CEO, Mr Martin Waleij adds; “I am delighted to work with established neurologists in the NHS to further develop and appraise our new medical device for the treatment of migraines”.

The study is now live and is planned to conclude by mid 2018, with participation lasting 3-4 months. If you are interested in getting involved in this research and would like more information, please e-mail: research@cumbria.nhs.uk or ring 07920 288244 / 01228 603145. 

Opportunity and invite for Alzheimer’s patients & carers to take part

1) Alzheimer’s Disease Genetics

This study looks at genetic factors (inheritance of DNA) and their potential role in Alzheimer’s disease.

It involves a one-hour visit for patient & carer, during which one blood sample and a questionnaire needs to be completed (may be done with supervision; visit can be split in two)

2) MODEM – Eye movement for diagnosis

This study looks into how eye movement may be used as a diagnostic tool for Alzheimer’s disease. No involvement for carers, apart from giving assent for patient to enrol.

It involves a two-hour visit for the patient, during which a non-invasive eye-test will be undertaken and some questionnaires are completed (again, with supervision if indicated)

3) Caring For Me & You – CBT for Carers

This study helps carers with coping strategies, as it can be very stressful caring for someone with dementia. Oxford Health NHS Foundation Trust and the Alzheimer’s Society have developed an online therapy called ‘Caring for Me and You’ which can be accessed from home.

TRIALNET - Natural History Study of the Development of Type 1 Diabetes

Led by the National Institute of Health, Type 1 Diabetes TrialNet is an international network of researchers dedicated to the study, prevention and early treatment of Type 1 Diabetes. TrialNet conducts studies to:

  • Learn more about the factors that put some people at risk for developing Type 1 Diabetes
  • Test treatments that could help delay or prevent Type 1 Diabetes
  • Test treatments that could help people keep producing their own insulin after they develop Type 1 Diabetes

To learn more about TrialNet screening and studies visit: www.DiabetesTrialNet.org

ADDRESS-2

The purpose of the study is to identify people newly diagnosed with Type 1 Diabetes, and the siblings of people with Type 1 Diabetes, who might be interested in taking part in future Diabetes research studies. We would like to collect information and blood samples from these people to understand more about the development and progression of Type 1 Diabetes, and to help find suitable trials of new treatments or other studies into Diabetes that they might want to take part in. When we find suitable trials or Diabetes studies, we will write to the eligible people to ask if they would be interested in taking part.

Making Research Better

The Making Research Better website has been created in partnership with patients and the public in the North and North East of Cumbria. The website will let you find out about clinical research and hear people’s stories of being involved in research. You can read about regional news and events that you can attend and find ways to become involved in clinical research studies. This could include:

Taking part in clinical research trials
Reviewing, commenting on or contributing to clinical study documents
Being a member of a patient group or study committee
Collecting or analysing study data
Writing up or communicating/sharing study findings

You can get involved in making research better by visiting the Making Research Better website